The AFC South entered the 2011 NFL season with several teams capable of competing for the division title. The Indianapolis Colts remained the biggest question mark due to health concerns around key players, while the Houston Texans looked ready to challenge for the top spot with an explosive offense.

Meanwhile, the Tennessee Titans focused on rebuilding with younger talent, and the Jacksonville Jaguars aimed to stay competitive through strong defense and disciplined football. Analysts expected the division race to remain close throughout the season, with injuries and consistency likely deciding the final standings.